Bone marrow signal during PET imaging in Hodgkin lymphoma

Markers of Bone Marrow Infiltration in Non-Hodgkin Lymphoma

Objective: To determine the levels of serum lactate dehydrogenase 2 (LD2) Isoenzyme and β2 microglobulin (β2m) in patients of non-Hodgkin’s lymphoma (NHL) and to correlate these levels in NHL patients with and without bone marrow infiltration. Study Design: Cross sectional study. Place and Duration of Study: Post Graduate Medical Institute, Lahore and Centre of Excellence in Molecular Biology (...

Discordant bone marrow involvement in non-Hodgkin lymphoma.

A discordant lymphoma occurs where 2 distinct histologic subtypes coexist in at least 2 separate anatomic sites. Histologic discordance is most commonly observed between the bone marrow (BM) and lymph nodes (LNs), where typically aggressive lymphoma is found in a LN biopsy with indolent lymphoma in a BM biopsy. Although the diagnosis of discordance relied heavily on histopathology alone in the ...

Bone marrow necrosis in a patient with non-Hodgkin lymphoma.

Bone marrow necrosis is a rare but ominous finding in various malignant and nonmalignant disorders. It is usually a postmortem diagnosis, but with the advent of modern imaging methods and clinical suspicion, bone marrow necrosis can be diagnosed as antemortem, especially in malignant disorders. We report a 60-years old man with newly diagnosed non-Hodgkin lymphoma presenting with anemia and ver...

Granulomatous bone marrow involvement of Hodgkin lymphoma, nodular sclerosis type

PET/CT in Evaluation Bone Marrow Infiltration in Malignant Lymphoma

Bone marrow stroma contains multi-potential non-hematopoietic progenitor cells capable of differentiating into various tissues of mesenchymal origin, including osteoblasts, endothelial cells, reticular cells, fibroblasts and adipocytes. The bone marrow's microvasculature with a single layer endothelium forms sinusoid, which radically distributes around the draining central sinus. The vasculatur...